Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma

Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma

We investigated the anticancer effect of disulfiram and metformin combination on fibrosarcoma in hamsters. Hamsters of both sexes (~ 70 g) were randomly allocated to control and experimental groups (8 animals per group). In all 10 groups, 2 × 106 BHK-21/C13 cells in 1 ml were injected subcutaneously...

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Bibliographic Details
Main Authors: Kosta J. Popović, Dušica J. Popović, Dejan Miljković, Jovan K. Popović, Dušan Lalošević, Mihalj Poša, Ivan Čapo
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Disulfiram
Metformin
Nitroglycerin
Mebendazole
Hamsters
Fibrosarcoma
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221009525

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http://www.sciencedirect.com/science/article/pii/S0753332221009525

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