Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis

<p>Abstract</p> <p>Objectives</p> <p>Stroke is a devastating complication after coronary artery bypass grafting, occurring in 1.4% to 4.3% of patients. A major cause of stroke is cerebral embolization of aortic atheromatous debris or calcified plaques. This report analy...

Full description

Bibliographic Details
Main Authors: Hilker Michael, Arlt Mathias, Keyser Andreas, Schopka Simon, Klose Alexander, Diez Claudius, Schmid Christof
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Journal of Cardiothoracic Surgery
Online Access:http://www.cardiothoracicsurgery.org/content/5/1/14
id doaj-33861b6fc8244e9dad709c5e9f006828
record_format Article
spelling doaj-33861b6fc8244e9dad709c5e9f0068282020-11-24T23:49:16ZengBMCJournal of Cardiothoracic Surgery1749-80902010-03-01511410.1186/1749-8090-5-14Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysisHilker MichaelArlt MathiasKeyser AndreasSchopka SimonKlose AlexanderDiez ClaudiusSchmid Christof<p>Abstract</p> <p>Objectives</p> <p>Stroke is a devastating complication after coronary artery bypass grafting, occurring in 1.4% to 4.3% of patients. A major cause of stroke is cerebral embolization of aortic atheromatous debris or calcified plaques. This report analyzes the incidence of stroke in patients treated according to the clampless concept, i.e. avoiding side-clamping of the aorta, by means of off-pump coronary artery bypass surgery (OPCAB) in combination with the HEARTSTRING device.</p> <p>Methods</p> <p>During a period of 43 months (2005-2008), 412 consecutive patients were treated with the above-mentioned method by one single surgeon. A minimum of one proximal aortal anastomosis was performed in each patient. Altogether, 542 proximal anastomosis were applied, each created by means of the HEARTSTRING device.</p> <p>Results</p> <p>The mean age of patients was 67+9.7 years, the predicted mortality 5.2% (logistic EuroSCORE) and the observed mortality 1.9%. Histories of preoperative neurological disorders or cerebrovascular diseases were documented in 15% of patients. The overall incidence of postoperative stroke was 0.48% in contrast to 1.3% according to the stroke risk score.</p> <p>Conclusions</p> <p>In accordance to previously published data, our results show that avoiding aortic side-clamping during OPCAB reduces postoperative stroke rates. The HEARTSTRING device is a safe option for creating proximal aortic anastomosis.</p> http://www.cardiothoracicsurgery.org/content/5/1/14
collection DOAJ
language English
format Article
sources DOAJ
author Hilker Michael
Arlt Mathias
Keyser Andreas
Schopka Simon
Klose Alexander
Diez Claudius
Schmid Christof
spellingShingle Hilker Michael
Arlt Mathias
Keyser Andreas
Schopka Simon
Klose Alexander
Diez Claudius
Schmid Christof
Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis
Journal of Cardiothoracic Surgery
author_facet Hilker Michael
Arlt Mathias
Keyser Andreas
Schopka Simon
Klose Alexander
Diez Claudius
Schmid Christof
author_sort Hilker Michael
title Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis
title_short Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis
title_full Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis
title_fullStr Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis
title_full_unstemmed Minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis
title_sort minimizing the risk of perioperative stroke by clampless off-pump bypass surgery: a retrospective observational analysis
publisher BMC
series Journal of Cardiothoracic Surgery
issn 1749-8090
publishDate 2010-03-01
description <p>Abstract</p> <p>Objectives</p> <p>Stroke is a devastating complication after coronary artery bypass grafting, occurring in 1.4% to 4.3% of patients. A major cause of stroke is cerebral embolization of aortic atheromatous debris or calcified plaques. This report analyzes the incidence of stroke in patients treated according to the clampless concept, i.e. avoiding side-clamping of the aorta, by means of off-pump coronary artery bypass surgery (OPCAB) in combination with the HEARTSTRING device.</p> <p>Methods</p> <p>During a period of 43 months (2005-2008), 412 consecutive patients were treated with the above-mentioned method by one single surgeon. A minimum of one proximal aortal anastomosis was performed in each patient. Altogether, 542 proximal anastomosis were applied, each created by means of the HEARTSTRING device.</p> <p>Results</p> <p>The mean age of patients was 67+9.7 years, the predicted mortality 5.2% (logistic EuroSCORE) and the observed mortality 1.9%. Histories of preoperative neurological disorders or cerebrovascular diseases were documented in 15% of patients. The overall incidence of postoperative stroke was 0.48% in contrast to 1.3% according to the stroke risk score.</p> <p>Conclusions</p> <p>In accordance to previously published data, our results show that avoiding aortic side-clamping during OPCAB reduces postoperative stroke rates. The HEARTSTRING device is a safe option for creating proximal aortic anastomosis.</p>
url http://www.cardiothoracicsurgery.org/content/5/1/14
work_keys_str_mv AT hilkermichael minimizingtheriskofperioperativestrokebyclamplessoffpumpbypasssurgeryaretrospectiveobservationalanalysis
AT arltmathias minimizingtheriskofperioperativestrokebyclamplessoffpumpbypasssurgeryaretrospectiveobservationalanalysis
AT keyserandreas minimizingtheriskofperioperativestrokebyclamplessoffpumpbypasssurgeryaretrospectiveobservationalanalysis
AT schopkasimon minimizingtheriskofperioperativestrokebyclamplessoffpumpbypasssurgeryaretrospectiveobservationalanalysis
AT klosealexander minimizingtheriskofperioperativestrokebyclamplessoffpumpbypasssurgeryaretrospectiveobservationalanalysis
AT diezclaudius minimizingtheriskofperioperativestrokebyclamplessoffpumpbypasssurgeryaretrospectiveobservationalanalysis
AT schmidchristof minimizingtheriskofperioperativestrokebyclamplessoffpumpbypasssurgeryaretrospectiveobservationalanalysis
_version_ 1725483170616311808