Residual NADPH Oxidase Activity and Isolated Lung Involvement in X-Linked Chronic Granulomatous Disease

Residual NADPH Oxidase Activity and Isolated Lung Involvement in X-Linked Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is characterized by inherited immune defects resulting from mutations in the NADPH oxidase complex genes. The X-linked type of CGD is caused by defects in the CYBB gene that encodes gp91-phox, a fundamental component of the NADPH oxidase complex. This mutation ori...

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Bibliographic Details
Main Authors: Maria J. Gutierrez, George D. McSherry, Faoud T. Ishmael, Alexandra A. Horwitz, Gustavo Nino
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2012/974561

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