IL-35 Regulates the Function of Immune Cells in Tumor Microenvironment

IL-35 Regulates the Function of Immune Cells in Tumor Microenvironment

Interleukin-35 (IL-35) is a heterodimeric cytokine composed of Epstein-Barr virus-induced gene 3 (EBI3) and IL-12p35 that has recently been shown to play diverse and important roles in the tumor microenvironment (TME). Owing to its immunosuppressive activity and ability to promote tumor growth and p...

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Bibliographic Details
Main Authors: Kewei Liu, Ai Huang, Jun Nie, Jun Tan, Shijie Xing, Yue Qu, Ke Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
tumor immunotherapy
regulatory immune cells
anti-tumor immunity
IL-35
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.683332/full

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