An ultrasensitive enzymatic method for measuring mevalonic acid in serum

We have developed a simple, precise, and ultrasensitive enzymatic method for measuring serum mevalonic acid (MVA) concentration, which is thought to be a good indicator of the in vivo cholesterol biosynthesis rate. This assay is based on an enzyme cycling reaction and makes use of HMG-CoA reductase...

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Bibliographic Details
Main Authors: Takeshi Matsuoka, Shigeru Ueda, Hideyuki Matsumoto, Masanobu Kawakami
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520418413