The Synergism of PGN, LTA and LPS in Inducing Transcriptome Changes, Inflammatory Responses and a Decrease in Lactation as Well as the Associated Epigenetic Mechanisms in Bovine Mammary Epithelial Cells

Mastitis is usually caused by a variety of pathogenic bacteria that include both Gram-positive and Gram-negative bacteria. Lipopolysaccharide (LPS) is the pathogen-associated molecular pattern (PAMP) of Gram-negative bacteria, and peptidoglycan (PGN) and lipoteichoic acid (LTA) are those of Gram-pos...

Full description

Bibliographic Details
Main Authors: Yongjiang Wu, Yawang Sun, Xianwen Dong, Jingbo Chen, Zili Wang, Juncai Chen, Guozhong Dong
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/6/387