Redox-Dependent Copper Ion Modulation of Amyloid-β (1-42) Aggregation In Vitro

Plaque deposits composed of amyloid-β (Aβ) fibrils are pathological hallmarks of Alzheimer’s disease (AD). Although copper ion dyshomeostasis is apparent in AD brains and copper ions are found co-deposited with Aβ peptides in patients’ plaques, the molecular effects of copper ion interactions and re...

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Bibliographic Details
Main Authors: Nima Sasanian, David Bernson, Istvan Horvath, Pernilla Wittung-Stafshede, Elin K. Esbjörner
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/6/924