The impact of miRNA target sites in coding sequences and in 3'UTRs.

Animal miRNAs are a large class of small regulatory RNAs that are known to directly and negatively regulate the expression of a large fraction of all protein encoding genes. The identification and characterization of miRNA targets is thus a fundamental problem in biology. miRNAs regulate target gene...

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Bibliographic Details
Main Authors: Zhuo Fang, Nikolaus Rajewsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3062573?pdf=render