Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis

• Main Authors: Manero Manuel, Olartecoechea Begoña, Royo Pedro, Alcázar Juan
• Format: Article
• Language: English
• Published: BMC 2009-11-01
• Series: Journal of Ovarian Research
• Online Access: http://www.ovarianresearch.com/content/2/1/18

<p>Abstract</p> <p>Objetive</p> <p>Thrombospondin-1 serum levels is correlate with pelvic pain in patients with ovarian endometriosis.</p> <p>Patients</p> <p>Thrombospondin-1 serum levels were prospectively analysed in 51 patients (group A asymptomatic patients or patients presenting mild dysmenorrhea and women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists among thrombospondin-1 serum levels and pelvic pain.</p> <p>Results</p> <p>From 56 patients, five cases were ultimateley excluded, because the histological diagnosis was other than cystic ovarian endometriosis (2 teratomas and 3 haemorragic cysts). The mean thrombospondin-1 serum levels in group A was 256,69 pg/ml_+37,07 and in group B was 291,41 pg/ml + 35,59.</p> <p>Conclusion</p> <p>Pain symptoms in ovarian endometriosis is not correlated with thrombospondin-1 serum levels.</p>