Kinesin Kif2C in regulation of DNA double strand break dynamics and repair

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair

DNA double strand breaks (DSBs) have detrimental effects on cell survival and genomic stability, and are related to cancer and other human diseases. In this study, we identified microtubule-depolymerizing kinesin Kif2C as a protein associated with DSB-mimicking DNA templates and known DSB repair pro...

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Bibliographic Details
Main Authors: Songli Zhu, Mohammadjavad Paydar, Feifei Wang, Yanqiu Li, Ling Wang, Benoit Barrette, Tadayoshi Bessho, Benjamin H Kwok, Aimin Peng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
Kif2C
MCAK
DNA repair
mobility
dynamics
Online Access:https://elifesciences.org/articles/53402

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