Platelets recognize brain-specific glycolipid structures, respond to neurovascular damage and promote neuroinflammation.

Platelets recognize brain-specific glycolipid structures, respond to neurovascular damage and promote neuroinflammation.

Platelets respond to vascular damage and contribute to inflammation, but their role in the neurodegenerative diseases is unknown. We found that the systemic administration of brain lipid rafts induced a massive platelet activation and degranulation resulting in a life-threatening anaphylactic-like r...

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Bibliographic Details
Main Authors: Ilya Sotnikov, Tatyana Veremeyko, Sarah C Starossom, Natalia Barteneva, Howard L Weiner, Eugene D Ponomarev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608633?pdf=render

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