Essential roles of mitochondrial and heme function in lung cancer bioenergetics and tumorigenesis

Essential roles of mitochondrial and heme function in lung cancer bioenergetics and tumorigenesis

Abstract Contrary to Warburg’s hypothesis, mitochondrial oxidative phosphorylation (OXPHOS) contributes significantly to fueling cancer cells. Several recent studies have demonstrated that radiotherapy-resistant and chemotherapy-resistant cancer cells depend on OXPHOS for survival and progression. S...

Full description

Bibliographic Details
Main Authors: Sarada Preeta Kalainayakan, Keely E. FitzGerald, Purna Chaitanya Konduri, Chantal Vidal, Li Zhang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Cell & Bioscience
Online Access:http://link.springer.com/article/10.1186/s13578-018-0257-8

Similar Items

Similar Items