Evaluation of the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer

• Main Authors: Wang H, Mao X
• Format: Article
• Language: English
• Published: Dove Medical Press 2020-06-01
• Series: Drug Design, Development and Therapy
• Subjects: neoadjuvant chemotherapy; breast cancer; evaluations of response
• Online Access: https://www.dovepress.com/evaluation-of-the-efficacy-of-neoadjuvant-chemotherapy-for-breast-canc-peer-reviewed-article-DDDT

Huan Wang, Xiaoyun Mao Department of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province, People’s Republic of ChinaCorrespondence: Xiaoyun MaoDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, 155 Nanjing North Street, Heping District, Shenyang City, Liaoning Province 110001, People’s Republic of ChinaTel/ Fax [phone]Email [e-mail]: Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on breast cancer biology, prognosis, and guidance for further therapy. Moreover, pathologic complete response is a validated and valuable surrogate prognostic factor of survival after therapy. Evaluations of neoadjuvant chemotherapy response are very important in clinical work and basic research. In this review, we will elaborate on evaluations of the efficacy of neoadjuvant chemotherapy in breast cancer and provide a clinical evaluation procedure for neoadjuvant chemotherapy.Keywords: neoadjuvant chemotherapy, breast cancer, evaluations of response