Macro-CK in carbon monoxide poisoning: A guide for in-hospital mortality?

• Main Authors: Erdal Tekin, Oktay Gulcu, Ugur Aksu, Mustafa Bayraktar
• Format: Article
• Language: English
• Published: Society of TURAZ AKADEMI 2021-09-01
• Series: Medicine Science
• Subjects: poisoning; cardiotoxic; mortality; creatine kinase; toxicity
• Online Access: http://www.ejmanager.com/fulltextpdf.php?mno=49196

Carbon monoxide (CO) poisoning is common in developing countries and can be mortal. CO poisoning can present with various signs and symptoms. In addition, it has been observed that some people have increased cardiovascular diseases and are associated with high mortality. In this study, the usability of Macro creatine-kinase (Macro-CK) for in-hospital mortality detection in CO poisoning was investigated. This study is a retrospective and single-center study. Data of patients diagnosed with CO poisoning were accessed from the hospital automation system. Macro-CK was accepted for patients with CK-MB higher than total CK. The patients were divided into two groups according to the Macro-CK determination. Macro-CK detected patients were arranged as group-1, and the others as group-2. In-hospital mortality rates were determined in the groups and compared between groups and analyzed. 1100 patients were eligible for the study. Of these patients, Macro-CK was detected in 33 patients (0.03%). The mean age of the patients was 37.6 ± 16.9 and 43.2% were male. In-hospital mortality was 20 (60.6%) in group 1, and 50 (4.7%) in group 2 and was statistically significant (p [Med-Science 2021; 10(3.000): 714-9]