Roles of NK Cell Receptors 2B4 (CD244), CS1 (CD319), and LLT1 (CLEC2D) in Cancer

Roles of NK Cell Receptors 2B4 (CD244), CS1 (CD319), and LLT1 (CLEC2D) in Cancer

Natural killer (NK) cells play a pivotal role in the immune system, especially in the recognition and clearance of cancer cells and infected cells. Their effector function is controlled by a delicate balance between the activating and inhibitory signals. We have identified 2B4 (CD244, SLAMF4) and CS...

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Bibliographic Details
Main Authors: Casey W. Buller, Porunelloor A. Mathew, Stephen O. Mathew
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
natural killer (NK) cells
2B4
CS1
LLT1
cancer
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/12/7/1755

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