The Drosophila KIF1A homolog unc-104 is important for site-specific active zone maturation

The Drosophila KIF1A homolog unc-104 is important for site-specific active zone maturation

Abstract Mutations in the kinesin-3 family member KIF1A have been associated with hereditary spastic paraplegia, hereditary sensory and autonomic neuropathy type 2 and intellectual disability. Both autosomal recessive and autosomal dominant forms of inheritance have been reported. Loss of KIF1A or i...

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Bibliographic Details
Main Authors: Yao V. Zhang, Shabab B. Hannan, Zeenna A. Stapper, Jeannine V. Kern, Thomas R. Jahn, Tobias M. Rasse
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Drosophila
Synapses
Synaptic Vesicles
NMJ
Rab3
hereditary spastic paraplegia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00207/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00207/full

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