Impact of Safety-Related Dose Reductions or Discontinuations on Sustained Virologic Response in HCV-Infected Patients: Results from the GUARD-C Cohort.

Impact of Safety-Related Dose Reductions or Discontinuations on Sustained Virologic Response in HCV-Infected Patients: Results from the GUARD-C Cohort.

Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings. The non-randomized GUARD-C cohort investigated baseline predictors of safety-related dose reductions or disco...

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Main Authors: Graham R Foster, Carmine Coppola, Moutaz Derbala, Peter Ferenci, Alessandra Orlandini, K Rajender Reddy, Ludovico Tallarico, Mitchell L Shiffman, Silke Ahlers, Georgios Bakalos, Tarek Hassanein, GUARD-C Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4809570?pdf=render

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