Utilization and control of ecological interactions in polymicrobial infections and community-based microbial cell factories [version 1; referees: 3 approved]

Microbial activities are most often shaped by interactions between co-existing microbes within mixed-species communities. Dissection of the molecular mechanisms of species interactions within communities is a central issue in microbial ecology, and our ability to engineer and control microbial commu...

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Bibliographic Details
Main Authors: Vinoth Wigneswaran, Cristina Isabel Amador, Lotte Jelsbak, Claus Sternberg, Lars Jelsbak
Format: Article
Language:English
Published: F1000 Research Ltd 2016-03-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-421/v1
Description
Summary:Microbial activities are most often shaped by interactions between co-existing microbes within mixed-species communities. Dissection of the molecular mechanisms of species interactions within communities is a central issue in microbial ecology, and our ability to engineer and control microbial communities depends, to a large extent, on our knowledge of these interactions. This review highlights the recent advances regarding molecular characterization of microbe-microbe interactions that modulate community structure, activity, and stability, and aims to illustrate how these findings have helped us reach an engineering-level understanding of microbial communities in relation to both human health and industrial biotechnology.
ISSN:2046-1402