Systemic ST6Gal-1 Is a Pro-survival Factor for Murine Transitional B Cells

Humoral immunity depends on intrinsic B cell developmental programs guided by systemic signals that convey physiologic needs. Aberrant cues or their improper interpretation can lead to immune insufficiency or a failure of tolerance and autoimmunity. The means by which such systemic signals are conve...

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Bibliographic Details
Main Authors: Eric E. Irons, Joseph T. Y. Lau
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02150/full