Type III Secretion Protein, PcrV, Impairs Pseudomonas aeruginosa Biofilm Formation by Increasing M1 Macrophage-Mediated Anti-bacterial Activities

Type III Secretion Protein, PcrV, Impairs Pseudomonas aeruginosa Biofilm Formation by Increasing M1 Macrophage-Mediated Anti-bacterial Activities

Pseudomonas aeruginosa biofilms employ a variety of strategies to hijack the host immune defense system to achieve chronic infection. However, the bacterial components that are involved in this process are not yet fully understood. PcrV, a needle tip protein of the P. aeruginosa type III secretion s...

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Bibliographic Details
Main Authors: Hua Yu, Junzhi Xiong, Jing Qiu, Xiaomei He, Halei Sheng, Qian Dai, Defeng Li, Rong Xin, Lu Jiang, Qiaoqiao Li, Qian Chen, Jin Peng, Maolin Wang, Xiancai Rao, Kebin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Microbiology
Subjects:
Pseudomonas aeruginosa
biofilm
PcrV
immune evasion
macrophage polarization
biofilm eradication
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01971/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01971/full

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