Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites <i>N</i>-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils

Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites <i>N</i>-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils

The endocannabinoids 2-arachidonoyl-glycerol and <i>N</i>-arachidonoyl-ethanolamine are lipids regulating many physiological processes, notably inflammation. Endocannabinoid hydrolysis inhibitors are now being investigated as potential anti-inflammatory agents. In addition to 2-arachidon...

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Bibliographic Details
Main Authors: Anne-Sophie Archambault, Francesco Tinto, Élizabeth Dumais, Volatiana Rakotoarivelo, Magdalena Kostrzewa, Pier-Luc Plante, Cyril Martin, Mélissa Simard, Cristoforo Silvestri, Roxane Pouliot, Michel Laviolette, Louis-Philippe Boulet, Rosa Maria Vitale, Alessia Ligresti, Vincenzo Di Marzo, Nicolas Flamand
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
endocannabinoid
linoleic acid
linoleoyl-glycerol
13-HODE
2-arachidonoyl-glycerol
anandamide
Online Access:https://www.mdpi.com/2073-4409/10/9/2322

Internet

https://www.mdpi.com/2073-4409/10/9/2322

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