Variability in detection and quantification of interferon β-1b–induced neutralizing antibodies

Variability in detection and quantification of interferon β-1b–induced neutralizing antibodies

<p>Abstract</p> <p>Background</p> <p>Interferon-beta (IFNB) therapy for multiple sclerosis can lead to the induction of neutralizing antibodies (NAbs) against IFNB. Various methods are used for detection and quantification of NAbs.</p> <p>Methods</p> &...

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Bibliographic Details
Main Authors: Hartung Hans-Peter, Kieseier Bernd, Goodin Douglas S, Arnason Barry GW, Comi Giancarlo, Cook Stuart, Filippi Massimo, Jeffery Douglas R, Kappos Ludwig, Bogumil Timon, Stemper Brigitte, Sandbrink Rupert, Nakada Yukiko, Nakajima Haruhiko, Schwenke Susanne, Lehr Stephan, Heubach Jürgen, Pohl Christoph, Reischl Joachim
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Clinical trials randomized controlled
IFNB-1b
Interferon beta
Neutralizing antibodies
Round robin
Online Access:http://www.jneuroinflammation.com/content/9/1/129

Internet

http://www.jneuroinflammation.com/content/9/1/129

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