Association Between BDNF Val66Met Polymorphism and Mild Behavioral Impairment in Patients With Parkinson's Disease

Neuropsychiatric symptoms (NPS) are common in Parkinson's disease (PD) and have demonstrated an association with the p. Val66Met, a polymorphism in the BDNF gene. Mild behavioral impairment (MBI) is a validated syndrome describing emergent and persistent NPS in older adults as a marker of poten...

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Main Authors: Mehrafarin Ramezani, Jennifer A. Ruskey, Kristina Martens, Mekale Kibreab, Zainul Javer, Iris Kathol, Tracy Hammer, Jenelle Cheetham, Etienne Leveille, Davide Martino, Justyna R. Sarna, Ziv Gan-Or, Gerald Pfeffer, Zahinoor Ismail, Oury Monchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.587992/full