Natural diterpenes from coffee, cafestol and kahweol induce apoptosis through regulation of specificity protein 1 expression in human malignant pleural mesothelioma

Natural diterpenes from coffee, cafestol and kahweol induce apoptosis through regulation of specificity protein 1 expression in human malignant pleural mesothelioma

<p>Abstract</p> <p>Background</p> <p>Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with a very poor prognosis. Several clinical studies such as immunotherapy, gene therapy and molecular targeting agents have been tried for treatment of malignant mes...

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Bibliographic Details
Main Authors: Lee Kyung-Ae, Chae Jung-Il, Shim Jung-Hyun
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Biomedical Science
Subjects:
Coffee
Cafestol
Kahweol
Apoptosis
Sp1
Human malignant pleural mesothelioma
Online Access:http://www.jbiomedsci.com/content/19/1/60

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