Screening of Key Fungal Strains in the Fermentation Process of the Chinese Medicinal Preparation “Lianzhifan Solution” Based on Metabolic Profiling and High-Throughput Sequencing Technology

Screening of Key Fungal Strains in the Fermentation Process of the Chinese Medicinal Preparation “Lianzhifan Solution” Based on Metabolic Profiling and High-Throughput Sequencing Technology

“Lianzhifan solution” (LZF) is produced by the natural fermentation of coptis root and gardenia fruit, and it is a classic prescription for external use in anorectal department. During the fermentation process, the structural evolution of microbial communities led to significant changes in the chemi...

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Bibliographic Details
Main Authors: Jie Xie, Yang Ye, Ze Wu, Xun Gou, Tong Peng, Xuegang Yuan, Xiangdong Yang, Xiaoyu Zhang, Quekun Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Microbiology
Subjects:
traditional Chinese medicine fermentation
key strain screening
equivalence evaluation
chemical metabolic profiling
iridoids
high-throughput sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.727968/full

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