Resveratrol ameliorates the anxiety- and depression-like behavior of subclinical hypothyroidism rat: possible involvement of the HPT axis, HPA axis, and Wnt/β-catenin pathway

Resveratrol ameliorates the anxiety- and depression-like behavior of subclinical hypothyroidism rat: possible involvement of the HPT axis, HPA axis, and Wnt/β-catenin pathway

Metabolic disease subclinical hypothyroidism (SCH) is closely associated with depression-like behavior both in human and animal studies, and our previous studies have identified the antidepressant effect of resveratrol (RES) in stressed rat model. The aim of this study was to investigate whether RES...

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Bibliographic Details
Main Authors: Jinfang eGe, Xu Ya Yun, Qin eGan, Jiang-Qun eChen, Fei-Hu eChen
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Endocrinology
Subjects:
Depression
resveratrol
subclinical hypothyroidism
Hypothalamus–pituitary–adrenal (HPA) axis
Hypothalamic–pituitary–thyroid (HPT) axis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00044/full

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