EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)

The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory to classic immunosuppressive agents and blockers of tumor necrosis factor (TNF) is presented in this article. Successful clinical use of biological agent rituximab was described. extraarticular symptoms of...

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Main Authors: E.I. Alexeeva, E.L. Semikina, T.M. Bzarova, S.I. Valieva, R.V. Denisova, A.O. Lisitsin, E.Yu. Gudkova, S.S. Akulova, E.A. Kopyl'tsova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2008-06-01
Series:Voprosy Sovremennoj Pediatrii
Online Access:https://vsp.spr-journal.ru/jour/article/view/1402
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spelling doaj-32ded64e52544fc9b7858bacba30c6622021-07-28T21:15:41Zeng"Paediatrician" Publishers LLC Voprosy Sovremennoj Pediatrii1682-55271682-55352008-06-017379851402EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)E.I. Alexeeva0E.L. Semikina1T.M. Bzarova2S.I. Valieva3R.V. Denisova4A.O. Lisitsin5E.Yu. Gudkova6S.S. Akulova7E.A. Kopyl'tsova8Scientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children's Health, Russian Academy of Medical Sciences, MoscowThe case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory to classic immunosuppressive agents and blockers of tumor necrosis factor (TNF) is presented in this article. Successful clinical use of biological agent rituximab was described. extraarticular symptoms of disease were stopped by 6 week of treatment, and acute inflammatory alteration of articulations was reduced by 16 week, the range of motions was completely restored. This case report demonstrates high activity of rituximab. A clinical and laboratory remission of disease in patient with severe course of systemic juvenile rheumatoid arthritis continues for a 32 weeks.Key words: children, juvenile rheumatoid arthritis, rituximab.https://vsp.spr-journal.ru/jour/article/view/1402
collection DOAJ
language English
format Article
sources DOAJ
author E.I. Alexeeva
E.L. Semikina
T.M. Bzarova
S.I. Valieva
R.V. Denisova
A.O. Lisitsin
E.Yu. Gudkova
S.S. Akulova
E.A. Kopyl'tsova
spellingShingle E.I. Alexeeva
E.L. Semikina
T.M. Bzarova
S.I. Valieva
R.V. Denisova
A.O. Lisitsin
E.Yu. Gudkova
S.S. Akulova
E.A. Kopyl'tsova
EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)
Voprosy Sovremennoj Pediatrii
author_facet E.I. Alexeeva
E.L. Semikina
T.M. Bzarova
S.I. Valieva
R.V. Denisova
A.O. Lisitsin
E.Yu. Gudkova
S.S. Akulova
E.A. Kopyl'tsova
author_sort E.I. Alexeeva
title EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)
title_short EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)
title_full EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)
title_fullStr EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)
title_full_unstemmed EXPERIENCE OF CLINICAL USE OF RITUXIMAB IN PATIENT WITH SYSTEMIC JUVENILE ARTHRITIS (A CASE REPORT)
title_sort experience of clinical use of rituximab in patient with systemic juvenile arthritis (a case report)
publisher "Paediatrician" Publishers LLC
series Voprosy Sovremennoj Pediatrii
issn 1682-5527
1682-5535
publishDate 2008-06-01
description The case of early onset and severe course of systemic juvenile rheumatoid arthritis refractory to classic immunosuppressive agents and blockers of tumor necrosis factor (TNF) is presented in this article. Successful clinical use of biological agent rituximab was described. extraarticular symptoms of disease were stopped by 6 week of treatment, and acute inflammatory alteration of articulations was reduced by 16 week, the range of motions was completely restored. This case report demonstrates high activity of rituximab. A clinical and laboratory remission of disease in patient with severe course of systemic juvenile rheumatoid arthritis continues for a 32 weeks.Key words: children, juvenile rheumatoid arthritis, rituximab.
url https://vsp.spr-journal.ru/jour/article/view/1402
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