Pinus kesiya Royle ex Gordon induces apoptotic cell death in hepatocellular carcinoma HepG2 cell via intrinsic pathway by PARP and Topoisomerase I suppression

Pinus kesiya Royle ex Gordon induces apoptotic cell death in hepatocellular carcinoma HepG2 cell via intrinsic pathway by PARP and Topoisomerase I suppression

Pinus kesiya Royle ex Gordon (PK), widely found in Southeast Asia, has been traditionally used for the treatment of several illnesses. Our previous studies showed that PK was highly cytotoxicity against liver cancer cells. The detailed mechanism of anticancer action of 50% hydro-ethanolic extract of...

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Bibliographic Details
Main Authors: Piman Pocasap, Apiyada Nonpunya, Natthida Weerapreeyakul
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Pinus kesiya Royle ex Gordon
HepG2
Terpenes
Apoptosis
Intrinsic pathway
Topoisomerase I
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221004133

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