Clinicopathological Characteristics and Survival Status of Male Breast Cancer: A Single Center Experience

• Main Authors: Seyed Mostafa Shiryazdi, Nazila Abrishami
• Format: Article
• Language: English
• Published: West Asia Organization for Cancer Prevention 2017-09-01
• Series: Asian Pacific Journal of Cancer Biology
• Online Access: http://www.waocp.org/journal/index.php/apjcb/article/view/59

Male breast cancer is a rare condition which causes to underlying mechanism is not well understood. Therefore, we have conducted this study to survey the clinicopathological characteristics of a series of male breast cancer consecutively treated in Yazd, Iran over a 15-year period. We retrospectively analyzed clinicopathological characteristics in a cohort of 39 male breast cancer patients who were surgically treated at the Shahid Sadoughi Hospital, Yazd, Iran, between 2001 and 2016. The demographic data, age, histology, disease stage, hormone receptor (HR) status, overall survival status, surgery treatment procedures, adjutant treatment, and tumor stage were registered. A total of 39 male breast cancer patients were included. The median age at diagnosis was 57.92 years (range, 21-95 years). Eight male breast cancer patients (20.5%) had a family history of breast cancer. The collective 2-, 5- and 10-year survival in our cohort was 83.4%, 43.2% and 10.3%, respectively. The disease stage significantly associated with overall survival (p=0.001). In our cohort the median age at diagnosis and survival rates was lower than previous reports. Moreover, the disease stage was a main independent prognostic factor for survival. Further studies are required to understand the factors that affect male breast cancer.