The <it>HAC1 </it>gene from <it>Pichia pastoris</it>: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins

The <it>HAC1 </it>gene from <it>Pichia pastoris</it>: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins

<p>Abstract</p> <p>Background</p> <p>The unfolded protein response (UPR) in eukaryotes upregulates factors that restore ER homeostasis upon protein folding stress and in yeast is activated by a non-conventional splicing of the <it>HAC1 </it>mRNA. The spliced...

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Bibliographic Details
Main Authors: Jacobs Pieter P, Ryckaert Stefan, Guerfal Mouna, Ameloot Paul, Van Craenenbroeck Kathleen, Derycke Riet, Callewaert Nico
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/9/1/49

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http://www.microbialcellfactories.com/content/9/1/49

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