Sequential Modulations of Tumor Vasculature and Stromal Barriers Augment the Active Targeting Efficacy of Antibody‐Modified Nanophotosensitizer in Desmoplastic Ovarian Carcinoma

Sequential Modulations of Tumor Vasculature and Stromal Barriers Augment the Active Targeting Efficacy of Antibody‐Modified Nanophotosensitizer in Desmoplastic Ovarian Carcinoma

Abstract Active‐targeted nanoparticles are attractive carriers due to their potentials to facilitate specific delivery of drugs into tumor cells while sparing normal cells. However, the therapeutic outcomes of active‐targeted nanomedicines are hampered by the multiple physiological barriers in the t...

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Bibliographic Details
Main Authors: Yue Yan, Binlong Chen, Zenghui Wang, Qingqing Yin, Yaoqi Wang, Fangjie Wan, Yulin Mo, Bo Xu, Qiang Zhang, Siling Wang, Yiguang Wang
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Advanced Science
Subjects:
active tumor targeting
antibody‐modified nanophotosensitizer
nonspecific uptake
stromal barriers
tumor accumulation
Online Access:https://doi.org/10.1002/advs.202002253

Internet

https://doi.org/10.1002/advs.202002253

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