VLPs Derived from the CCMV Plant Virus Can Directly Transfect and Deliver Heterologous Genes for Translation into Mammalian Cells

Virus-like particles (VLPs) are being used for therapeutic developments such as vaccines and drug nanocarriers. Among these, plant virus capsids are gaining interest for the formation of VLPs because they can be safely handled and are noncytotoxic. A paradigm in virology, however, is that plant viru...

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Main Authors: María V. Villagrana-Escareño, Elizabeth Reynaga-Hernández, Othir G. Galicia-Cruz, Ana L. Durán-Meza, Viridiana De la Cruz-González, Carmen Y. Hernández-Carballo, Jaime Ruíz-García
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2019/4630891