Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells.

Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells.

Alopecia is the common hair loss problem that can affect many people. However, current therapies for treatment of alopecia are limited by low efficacy and potentially undesirable side effects. We have identified a new function for valproic acid (VPA), a GSK3β inhibitor that activates the Wnt/β-caten...

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Bibliographic Details
Main Authors: Soung-Hoon Lee, Juyong Yoon, Seung Ho Shin, Muhamad Zahoor, Hyoung Jun Kim, Phil June Park, Won-Seok Park, Do Sik Min, Hyun-Yi Kim, Kang-Yell Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323655?pdf=render

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