Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron

<p>Abstract</p> <p>Background</p> <p>Iron overload is associated with liver toxicity, cirrhosis, and hepatocellular carcinoma in humans. While most iron circulates in blood as transferrin-bound iron, non-transferrin-bound iron (NTBI) also becomes elevated and contribute...

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Bibliographic Details
Main Authors: Messner Donald J, Kowdley Kris V
Format: Article
Language:English
Published: BMC 2008-02-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/8/2