Short-course antimicrobial therapy for paediatric respiratory infections (SAFER): study protocol for a randomized controlled trial

Short-course antimicrobial therapy for paediatric respiratory infections (SAFER): study protocol for a randomized controlled trial

Abstract Background Community-acquired pneumonia (CAP) is commonly diagnosed in children. The Infectious Disease Society of America guidelines recommend 10 days of high-dose amoxicillin for the treatment of non-severe CAP but 5-day “short course” therapy may be just as effective. Randomized trials i...

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Bibliographic Details
Main Authors: Jeffrey Pernica, Stuart Harman, April Kam, Jacob Bailey, Redjana Carciumaru, Sarah Khan, Martha Fulford, Lehana Thabane, Robert Slinger, Cheryl Main, Marek Smieja, Mark Loeb
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Trials
Subjects:
Community-acquired pneumonia
Antimicrobial stewardship
Amoxicillin
Microbiome
Respiratory virus
Streptococcus pneumoniae
Online Access:http://link.springer.com/article/10.1186/s13063-018-2457-2

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