Research Progress in Circulating Tumor Cells of Glioblastoma

• Main Authors: TAN Hu, LIU Chang, ZHANG Qingmei, XIAO Shaowen
• Format: Article
• Language: zho
• Published: Magazine House of Cancer Research on Prevention and Treatment 2018-12-01
• Series: Zhongliu Fangzhi Yanjiu
• Subjects: glioblastoma; circular marker; circulating tumor cells
• Online Access: http://html.rhhz.net/ZLFZYJ/html/8578.2018.18.0603.htm

Glioblastoma(GBM) is a highly malignant tumor. Despite various treatment modalities, such as surgery, radiotherapy and chemotherapy, most patients with GBM are still dying of its recurrence. The prognosis of patients with GBM is extremely poor, which is related to not only tumor cell invasion and proliferation, but also immature tumor monitoring methods. For a long time, many studies have found that circulating tumor cells(CTCs) can be detected in patients' blood. It plays an extremely important role in the recurrence of GBM. Therefore, the CTCs detection technology of glioblastoma and its clinical significance have been a hotspot in the present research.