Combined methods to evaluate human cells in muscle xenografts.

Combined methods to evaluate human cells in muscle xenografts.

Xenotransplantation of human cells into immunodeficient mouse models is a very powerful tool and an essential step for the pre-clinical evaluation of therapeutic cell- and gene- based strategies. Here we describe an optimized protocol combining immunofluorescence and real-time quantitative PCR to bo...

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Bibliographic Details
Main Authors: Mona Bensalah, Pierre Klein, Ingo Riederer, Soraya Chaouch, Laura Muraine, Wilson Savino, Gillian Sandra Butler-Browne, Capucine Trollet, Vincent Mouly, Anne Bigot, Elisa Negroni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211522

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