Homology and linkage in crossover for linear genomes of variable length.

The use of variable-length genomes in evolutionary computation has applications in optimisation when the size of the search space is unknown, and provides a unique environment to study the evolutionary dynamics of genome structure. Here, we revisit crossover for linear genomes of variable length, id...

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Main Authors: Adriaan Merlevede, Henrik Åhl, Carl Troein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209712
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spelling doaj-3299757fc9384021a9c3ed600e95b5422021-03-03T20:59:30ZengPublic Library of Science (PLoS)PLoS ONE1932-62032019-01-01141e020971210.1371/journal.pone.0209712Homology and linkage in crossover for linear genomes of variable length.Adriaan MerlevedeHenrik ÅhlCarl TroeinThe use of variable-length genomes in evolutionary computation has applications in optimisation when the size of the search space is unknown, and provides a unique environment to study the evolutionary dynamics of genome structure. Here, we revisit crossover for linear genomes of variable length, identifying two crucial attributes of successful recombination algorithms: the ability to retain homologous structure, and to reshuffle variant information. We introduce direct measures of these properties-homology score and linkage score-and use them to review existing crossover algorithms, as well as two novel ones. In addition, we measure the performance of these crossover methods on three different benchmark problems, and find that variable-length genomes out-perform fixed-length variants in all three cases. Our homology and linkage scores successfully explain the difference in performance between different crossover methods, providing a simple and insightful framework for crossover in a variable-length setting.https://doi.org/10.1371/journal.pone.0209712
collection DOAJ
language English
format Article
sources DOAJ
author Adriaan Merlevede
Henrik Åhl
Carl Troein
spellingShingle Adriaan Merlevede
Henrik Åhl
Carl Troein
Homology and linkage in crossover for linear genomes of variable length.
PLoS ONE
author_facet Adriaan Merlevede
Henrik Åhl
Carl Troein
author_sort Adriaan Merlevede
title Homology and linkage in crossover for linear genomes of variable length.
title_short Homology and linkage in crossover for linear genomes of variable length.
title_full Homology and linkage in crossover for linear genomes of variable length.
title_fullStr Homology and linkage in crossover for linear genomes of variable length.
title_full_unstemmed Homology and linkage in crossover for linear genomes of variable length.
title_sort homology and linkage in crossover for linear genomes of variable length.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2019-01-01
description The use of variable-length genomes in evolutionary computation has applications in optimisation when the size of the search space is unknown, and provides a unique environment to study the evolutionary dynamics of genome structure. Here, we revisit crossover for linear genomes of variable length, identifying two crucial attributes of successful recombination algorithms: the ability to retain homologous structure, and to reshuffle variant information. We introduce direct measures of these properties-homology score and linkage score-and use them to review existing crossover algorithms, as well as two novel ones. In addition, we measure the performance of these crossover methods on three different benchmark problems, and find that variable-length genomes out-perform fixed-length variants in all three cases. Our homology and linkage scores successfully explain the difference in performance between different crossover methods, providing a simple and insightful framework for crossover in a variable-length setting.
url https://doi.org/10.1371/journal.pone.0209712
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AT carltroein homologyandlinkageincrossoverforlineargenomesofvariablelength
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