New Faces of old Friends: Emerging new Roles of RNA-Binding Proteins in the DNA Double-Strand Break Response

New Faces of old Friends: Emerging new Roles of RNA-Binding Proteins in the DNA Double-Strand Break Response

DNA double-strand breaks (DSBs) are highly cytotoxic DNA lesions. To protect genomic stability and ensure cell homeostasis, cells mount a complex signaling-based response that not only coordinates the repair of the broken DNA strand but also activates cell cycle checkpoints and, if necessary, induce...

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Bibliographic Details
Main Authors: Julie A. Klaric, Stas Wüst, Stephanie Panier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
DNA double strand break
RNA-binding protein
genome stability
DNA repair
non-coding RNA
phase separation
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.668821/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.668821/full

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