Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy

Cellular senescence is characterized by irreversible growth arrest incurred through either replicative exhaustion or by pro-oncogenic cellular stressors (radioactivity, oxidative stress, oncogenic activation). The enrichment of senescent cells in tissues with age has been associated with tissue dysh...

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Bibliographic Details
Main Authors: Shashank Masaldan, Sharnel A.S. Clatworthy, Cristina Gamell, Zoe M. Smith, Paul S. Francis, Delphine Denoyer, Peter M. Meggyesy, Sharon La Fontaine, Michael A. Cater
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718300818