Quantitation of Pyrrole-Imidazole Polyamide in Rat Plasma by High-Performance Liquid Chromatography Coupled with UV Detection

Quantitation of Pyrrole-Imidazole Polyamide in Rat Plasma by High-Performance Liquid Chromatography Coupled with UV Detection

A simple and robust method using high-performance liquid chromatography with UV detection was developed and validated for the determination of six pyrrole-imidazole (PI) polyamides (HN.49, TGF-β1f, TGF-β1t, HN.50f, HN.50t, and LOX-1) in rat plasma. After the plasma proteins were precipitated with m...

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Bibliographic Details
Main Authors: Tomonori Kamei, Takahiko Aoyama, Chihiro Tanaka, Takafumi Nagashima, Yukio Aoyama, Hiroyuki Hayashi, Hiroki Nagase, Takahiro Ueno, Noboru Fukuda, Yoshiaki Matsumoto
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/715928

Internet

http://dx.doi.org/10.1155/2012/715928

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