Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes
Abstract Background Undercarboxylated osteocalcin (ucOC) is a secreted protein produced by osteoblasts that regulates insulin secretion and insulin sensitivity in rodents. However, the significance of these effects on glucose metabolism in human remains unknown. Moreover, the pathophysiological role...
Main Authors: | Shogo Funakoshi, Kumiko Yoshimura, Seiki Hirano, Satoko Ohmi, Eri Amano, Yoshiharu Fukuda, Yoshio Terada, Shimpei Fujimoto |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-08-01
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Series: | Diabetology & Metabolic Syndrome |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13098-020-00579-3 |
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