Exosome-transferred hsa_circ_0014235 promotes DDP chemoresistance and deteriorates the development of non-small cell lung cancer by mediating the miR-520a-5p/CDK4 pathway

Exosome-transferred hsa_circ_0014235 promotes DDP chemoresistance and deteriorates the development of non-small cell lung cancer by mediating the miR-520a-5p/CDK4 pathway

Abstract Background Circular RNAs (circRNAs) play crucial roles in the development and progression of human cancers, including non-small cell lung cancer (NSCLC). However, most of these circRNAs, such as hsa_circ_0014235, are not fully identified in functions and mechanisms. Methods The isolated exo...

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Bibliographic Details
Main Authors: Xueliang Xu, Rong Tao, Liying Sun, Xia Ji
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cancer Cell International
Subjects:
hsa_circ_0014235
Exosome
miR-520a-5p
CDK4
NSCLC
Online Access:http://link.springer.com/article/10.1186/s12935-020-01642-9

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http://link.springer.com/article/10.1186/s12935-020-01642-9

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