Summary: | In order to study the mechanical properties of new iliac vein stents in different stenotic vessels, the release process of four stents in iliac vein with different stenosis rates (normal, 30%, 50%, 70%) was simulated by finite element method, the influence of stenosis rate on the mechanical properties of stents was analyzed, and the safety of stents was verified by animal experiments. The results showed that the high stress-strain regions of the four stents were all located in the stenosis area. With the increase of the stenosis rate, the equivalent stress and elastic strain of the stents tended to increase. After fatigue calculation, the safety factor of the fatigue strength of the stent is more than 1, which meets the requirement of 10 years fatigue life. To establish an animal model of iliac vein stenosis, the endothelial cells were covered on the surface of the stent 90 days after stent implantation, the intima was proliferated obviously, and the mechanical properties and biocompatibility of the stent were stable. The new type of stent for iliac vein stenosis could be used as the main experimental instrument in later animal experiments.
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