IL-33 Prevents MLD-STZ Induction of Diabetes and Attenuate Insulitis in Prediabetic NOD Mice

IL-33 Prevents MLD-STZ Induction of Diabetes and Attenuate Insulitis in Prediabetic NOD Mice

Type 1 diabetes is an autoimmune disease caused by the immune-mediated destruction of pancreatic β-cells. Prevention of type 1 diabetes requires early intervention in the autoimmune process against beta-cells of the pancreatic islets of Langerhans, which is believed to result from disordered immunor...

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Bibliographic Details
Main Authors: Sladjana Pavlovic, Ivica Petrovic, Nemanja Jovicic, Biljana Ljujic, Marina Miletic Kovacevic, Nebojsa Arsenijevic, Miodrag L. Lukic
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
IL-33
diabetes
C57BL/6 mice
NOD mice
streptozotocin
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02646/full

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