NF-κB regulates caspase-4 expression and sensitizes neuroblastoma cells to Fas-induced apoptosis.

Found in neurons and neuroblastoma cells, Fas-induced apoptosis and accompanied activation of NF-κB signaling were thought to be associated with neurodegenerative diseases. However, the detailed functions of NF-κB activation in Fas killing and the effect of NF-κB activation on its downstream events...

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Bibliographic Details
Main Authors: Hai-Jie Yang, Mian Wang, Lei Wang, Bin-Feng Cheng, Xiao-Yu Lin, Zhi-Wei Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4335045?pdf=render