Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time

Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time

Objective: To determine the longitudinal relationship between monocyte chemotactic protein 1 (MCP-1)/CCL2 and memory function in older adults.Methods: We examined longitudinal plasma MCP-1/CCL2 levels and a longitudinal verbal memory measure (CVLT-II 20’ recall) in a sample of 399 asymptomatic older...

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Bibliographic Details
Main Authors: Brianne M. Bettcher, John Neuhaus, Matthew J. Wynn, Fanny M. Elahi, Kaitlin B. Casaletto, Rowan Saloner, Ryan Fitch, Anna Karydas, Joel H. Kramer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
chemokines
inflammation
CCL2
memory
longitudinal
cognitive aging
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00025/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2019.00025/full

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