CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts

CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts

Abstract Background Interaction between cancer cells and fibroblasts mediated by extracellular matrix metalloproteinase inducer (emmprin, CD147) is important in the invasion and proliferation of cancer cells. However, the exact mechanism of emmprin mediated stimulation of matrix metalloprotease-2 (M...

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Bibliographic Details
Main Authors: M. Aoki, K. Koga, M. Miyazaki, M. Hamasaki, N. Koshikawa, M. Oyama, H. Kozuka-Hata, M. Seiki, B. P. Toole, K. Nabeshima
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Cancer
Subjects:
Emmprin
CD73
MMP-2
Sarcoma
Fibroblasts
Online Access:http://link.springer.com/article/10.1186/s12885-019-6127-x

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http://link.springer.com/article/10.1186/s12885-019-6127-x

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