Pan-cancer identification of clinically relevant genomic subtypes using outcome-weighted integrative clustering

Abstract Background Comprehensive molecular profiling has revealed somatic variations in cancer at genomic, epigenomic, transcriptomic, and proteomic levels. The accumulating data has shown clearly that molecular phenotypes of cancer are complex and influenced by a multitude of factors. Conventional...

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Bibliographic Details
Main Authors: Arshi Arora, Adam B. Olshen, Venkatraman E. Seshan, Ronglai Shen
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Genome Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13073-020-00804-8