Dynamics of ceramide channels detected using a microfluidic system.

Ceramide, a proapoptotic sphingolipid, has been shown to form channels, in mitochondrial outer membranes, large enough to translocate proteins. In phospholipid membranes, electrophysiological studies and electron microscopic visualization both report that these channels form in a range of sizes with...

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Bibliographic Details
Main Authors: Chenren Shao, Bing Sun, Don L DeVoe, Marco Colombini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3440423?pdf=render